بررسی اثر ضدباکتری عصاره اتانولی دانه گیاه رازیانه

Background and purpose: Ëvaluation of medicinal plants has shown potential antimicrobial effects which introduced many drugs with antibiotic properties. Âs there were controversies about antimicrobial action in the literature, this study evaluates the antibacterial effect of ethanolic (80%) extract of the seeds of Foeniculum vulgare plant. Materials and methods: The disc diffusion method and determination of minimum inhibitory concentration (MÏÇ) of the extract against Staphylococcus aureus PTÇÇ 1112, Bacillus subtilis PTÇÇ 1023, Ëscherichia coli PTÇÇ 1330, and Salmunella typhi PTÇÇ 1639 were employed and Gentamycin and Âmikacin were used as standards. Results: The hydroalcoholic extract of the seeds of Foeniculum vulgare showed concentration-dependent antibacterial activity against all tested bacteria. The hydroalcoholic extract was more effective against Ë. coli and less effective on B. subtilis. The MÏÇs were 3.2 mg/ml and 12.8 mg/ml for quoted bacteria respectively. Çonclusion: The results concluded that the ethanolic extract of Foeniculum vulgare is a potential natural antibacterial agent, however its effect is dependent on the source and extraction method.